SIGLEC1 Rabbit Polyclonal Antibody (CAB17533)
- SKU:
- CAB17533
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SIGLEC1 Rabbit Polyclonal Antibody |
SKU: | CAB17533 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-300 of human SIGLEC1 (NP_075556.1). |
Sequence: | EVPD GITA IWYY DYSG QRQV VSHS ADPK LVEA RFRG RTEF MGNP EHRV CNLL LKDL QPED SGSY NFRF EISE VNRW SDVK GTLV TVTE EPRV PTIA SPVE LLEG TEVD FNCS TPYV CLQE QVRL QWQG QDPA RSVT FNSQ KFEP TGVG HLET LHMA MSWQ DHGR ILRC QLSV ANHR AQSE IHLQ VKYA PKGV KILL SPSG RNIL PGEL VTLT CQVN SSYP AVSS IKWL KDGV RLQT KTGV LHLP QAAW SDA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SN; CD169; SIGLEC-1; SIGLEC1 |
Positive Sample: | HepG2 |
Cellular Localization: | early endosome, extracellular region, late endosome, plasma membrane |
Calculated MW: | 183kDa |
Observed MW: | 200kDa |
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. The protein plays an important role in multiple human diseases and bacterial and viral infections has been shown to enhance SARS-CoV-2 infection.
Purification Method: | Affinity purification |
Gene ID: | 6614 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |