The Sideroflexin-3 Polyclonal Antibody (CAB12298) is a valuable tool for researchers studying Sideroflexin-3, a protein involved in iron metabolism and mitochondrial function. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the Sideroflexin-3 protein, this antibody allows for the detection and analysis of this important cellular component in a variety of cell types.Sideroflexin-3 plays a crucial role in cellular iron homeostasis, facilitating the transport of iron into the mitochondria for various metabolic processes. Dysregulation of Sideroflexin-3 has been implicated in disorders related to iron metabolism, as well as mitochondrial dysfunction and oxidative stress.
Research into Sideroflexin-3 may provide insights into the pathogenesis of diseases such as iron overload disorders, neurodegenerative diseases, and certain types of cancer.The Sideroflexin-3 Polyclonal Antibody is a valuable tool for investigating the function and regulation of this protein in normal and diseased states. Its specificity and sensitivity make it an ideal choice for studies focusing on iron metabolism, mitochondrial function, and related cellular processes. By using this antibody, researchers can gain a better understanding of the role of Sideroflexin-3 in health and disease, potentially leading to the development of novel therapeutic strategies targeting iron-related disorders.
Product Name:
SFXN3 Rabbit Polyclonal Antibody
SKU:
CAB12298
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human SFXN3 (NP_112233.2).
Enables serine transmembrane transporter activity. Involved in serine import into mitochondrion. Located in mitochondrion.
Purification Method:
Affinity purification
Gene ID:
81855
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using SFXN3 Rabbit pAb (CAB12298) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
