NEU1 Rabbit Polyclonal Antibody (CAB6299)
- SKU:
- CAB6299
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | NEU1 Rabbit Polyclonal Antibody |
SKU: | CAB6299 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-415 of human NEU1 (NP_000425.1). |
Sequence: | PRKG RLIV CGHG TLER DGVF CLLS DDHG ASWR YGSG VSGI PYGQ PKQE NDFN PDEC QPYE LPDG SVVI NARN QNNY HCHC RIVL RSYD ACDT LRPR DVTF DPEL VDPV VAAG AVVT SSGI VFFS NPAH PEFR VNLT LRWS FSNG TSWR KETV QLWP GPSG YSSL ATLE GSMD GEEQ APQL YVLY EKGR NHYT ESIS VAKI SVYG TL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | NEU; NANH; SIAL1; NEU1 |
Positive Sample: | BxPC-3,Mouse kidney,Mouse pancreas,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasmic vesicle, Lumenal side, Lysosome lumen, Lysosome membrane, Peripheral membrane protein. |
Calculated MW: | 45kDa |
Observed MW: | 45kDa |
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.
Purification Method: | Affinity purification |
Gene ID: | 4758 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |