The SHOC2 Polyclonal Antibody (CAB4199) is a valuable tool for researchers studying the SHOC2 protein, a key player in cellular signaling pathways. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.SHOC2, a scaffold protein, is involved in the Ras-MAPK signaling pathway, regulating cell growth, differentiation, and survival. Dysregulation of this pathway has been implicated in various diseases, including cancer, developmental disorders, and cardiovascular diseases.
The SHOC2 Polyclonal Antibody binds specifically to SHOC2, allowing for accurate detection and analysis in a variety of cell types.By understanding the role of SHOC2 in cellular signaling, researchers can gain insights into the molecular mechanisms underlying disease pathogenesis and potentially identify new therapeutic targets. The SHOC2 Polyclonal Antibody is a valuable tool for advancing research in cell biology, cancer biology, and drug discovery.
Product Name:
SHOC2 Rabbit Polyclonal Antibody
SKU:
CAB4199
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human SHOC2 (NP_031399.2).
This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair.
Purification Method:
Affinity purification
Gene ID:
8036
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SHOC2 Rabbit pAb (CAB4199) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
