[KO Validated] SHMT2 Rabbit Polyclonal Antibody (CAB1215)
- SKU:
- CAB1215
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | [KO Validated] SHMT2 Rabbit Polyclonal Antibody |
SKU: | CAB1215 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 265-504 of human SHMT2 (NP_005403.2). |
Sequence: | PSPF KHAD IVTT TTHK TLRG ARSG LIFY RKGV KAVD PKTG REIP YTFE DRIN FAVF PSLQ GGPH NHAI AAVA VALK QACT PMFR EYSL QVLK NARA MADA LLER GYSL VSGG TDNH LVLV DLRP KGLD GARA ERVL ELVS ITAN KNTC PGDR SAIT PGGL RLGA PALT SRQF REDD FRRV VDFI DEGV NIGL EVKS KTAK LQDF KSFL LKDS ETSQ RLAN LRQR VEQF ARAF PMPG FDEH |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | GLYA; SHMT; mSHMT; NEDCASB; HEL-S-51e; T2 |
Positive Sample: | HeLa,293T,SW620,HeLa,293F,Mouse kidney,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion, Mitochondrion inner membrane, Mitochondrion matrix, mitochondrion nucleoid. |
Calculated MW: | 56kDa |
Observed MW: | 56kDa |
This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 6472 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |