SHMT1 Rabbit Polyclonal Antibody (CAB12489)
- SKU:
- CAB12489
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | SHMT1 Rabbit Polyclonal Antibody |
SKU: | CAB12489 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 285-444 of human SHMT1 (NP_683718.1). |
Sequence: | FKVY QHQV VANC RALS EALT ELGY KIVT GGSD NHLI LVDL RSKG TDGG RAEK VLEA CSIA CNKN TCPG DRSA LRPS GLRL GTPA LTSR GLLE KDFQ KVAH FIHR GIEL TLQI QSDT GVRA TLKE FKER LAGD KYQA AVQA LREE VESF ASLF PLPG LPDF |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | SHMT; CSHMT; SHMT1 |
Positive Sample: | Mouse liver,Rat liver,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 53kDa |
Observed MW: | 50kDa |
This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 6470 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |