The Sharpin Polyclonal Antibody (CAB12240) is a valuable tool for researchers studying Sharpin, a protein involved in immune regulation and inflammation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the Sharpin protein, researchers can analyze and detect its presence in various cell types.Sharpin plays a key role in immune function by regulating inflammation and promoting immune homeostasis. Dysregulation of Sharpin has been implicated in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
By studying Sharpin using this antibody, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.Overall, the Sharpin Polyclonal Antibody is a valuable tool for researchers in immunology and cancer research seeking to understand the role of Sharpin in immune regulation and inflammation. Its specificity and sensitivity make it an ideal choice for studying Sharpin in a variety of research applications.
Product Name:
SHARPIN Rabbit Polyclonal Antibody
SKU:
CAB12240
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-126 of human SHARPIN (NP_112236.3?).
Enables polyubiquitin modification-dependent protein binding activity. Involved in protein linear polyubiquitination and regulation of signal transduction. Located in cytosol. Part of LUBAC complex.
Purification Method:
Affinity purification
Gene ID:
81858
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SHARPIN antibody (CAB12240) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
