The SH3BP4 Polyclonal Antibody (CAB14351) is a valuable tool for researchers studying the SH3BP4 protein, which plays a key role in intracellular signaling pathways. This antibody, produced in rabbits, is highly specific to human samples and is ideal for use in Western blotting and other immunological techniques.SH3BP4 is a protein involved in regulating cellular processes such as cell proliferation, apoptosis, and vesicle trafficking. Dysregulation of SH3BP4 has been linked to various diseases, including cancer and neurological disorders.
By using this polyclonal antibody, researchers can accurately detect and study SH3BP4 expression levels in different cell types, providing valuable insights into its function and potential therapeutic targets.With its high reactivity and specificity, the SH3BP4 Polyclonal Antibody is a valuable tool for research in cell biology, cancer biology, and neuroscience. By understanding the role of SH3BP4 in these contexts, researchers can pave the way for novel therapeutic interventions and treatment strategies.
Product Name:
SH3BP4 Rabbit Polyclonal Antibody
SKU:
CAB14351
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 784-963 of human SH3BP4 (NP_055336.1).
This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor.
Purification Method:
Affinity purification
Gene ID:
23677
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SH3BP4 Rabbit pAb (CAB14351) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
