SH3BP2 Rabbit Polyclonal Antibody (CAB10243)
- SKU:
- CAB10243
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SH3BP2 Rabbit Polyclonal Antibody |
SKU: | CAB10243 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 392-561 of human SH3BP2 (NP_001116153.1). |
Sequence: | VPEA MARP AVLP RPEK PQLP HLQR SPPD GQSF RSFS FEKP RQPS QADT GGDD SDED YEKV PLPN SVFV NTTE SCEV ERLF KATS PRGE PQDG LYCI RNSS TKSG KVLV VWDE TSNK VRNY RIFE KDSK FYLE GEVL FVSV GSMV EHYH THVL PSHQ SLLL RHPY GYTG PR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | 3BP2; CRBM; CRPM; 3BP-2; RES4-23; SH3BP2 |
Positive Sample: | A-549,Mouse spleen,Mouse lung |
Conjugate: | Unconjugated |
Calculated MW: | 62kDa |
Observed MW: | 75kDa/80kDa |
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6452 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |