The SH3BP1 Polyclonal Antibody (PACO12181) is a valuable tool for research involving SH3BP1, a protein involved in various cellular processes such as cell signaling and vesicle trafficking. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SH3BP1 protein, this antibody enables accurate detection and analysis in different cell types, making it ideal for studies in cell biology, signal transduction, and membrane dynamics.
SH3BP1 is a key player in cellular pathways that regulate cell growth, proliferation, and survival. Its involvement in critical cellular functions makes it a promising target for research related to cancer, neurodegenerative diseases, and other conditions involving abnormal cell signaling. Understanding the role of SH3BP1 can provide insights into potential therapeutic strategies for these diseases, making the SH3BP1 Polyclonal Antibody a valuable resource for researchers in the field.
SH3BP1: Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, Rac/Rho; Adaptor/scaffold; GAPsChromosomal Location of Human Ortholog: 22q13.1Molecular Function: protein binding
