The SH2D4A Polyclonal Antibody (PACO05005) is a valuable tool for researchers studying the SH2D4A protein, a member of the SH2 domain-containing protein family. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blotting applications. By specifically binding to the SH2D4A protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for investigations in immunology and cancer research.
SH2D4A, also known as ASB3, is involved in various cellular processes, including signal transduction and protein degradation. Its potential roles in immune regulation and tumor suppression make it a promising target for studying diseases such as cancer and autoimmune disorders. By delving into the functions of SH2D4A, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic strategies aimed at modulating immune responses.
Antibody Name:
SH2D4A Antibody (PACO05005)
Antibody SKU:
PACO05005
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:20000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human SH2D4A.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
SH2D4A; SH2A; SH2 domain-containing protein 4A; Protein SH(2)A
UniProt Protein Function:
SH2D4A: Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 8p21.2Cellular Component: cytoplasmMolecular Function: phosphatase binding; protein binding
