The SH2B1 Polyclonal Antibody (CAB5564) is a valuable tool for researchers studying SH2B1, a protein involved in regulating various cellular processes, including cell growth, differentiation, and metabolism. This antibody, raised in rabbits, is highly specific to SH2B1 and is validated for use in Western blot applications. By binding to SH2B1, this antibody allows for the detection and analysis of the protein in a wide range of cell types, making it ideal for studies in cell biology, metabolism, and signal transduction.SH2B1 is known to function as an adapter protein, playing a crucial role in signaling pathways that control cell proliferation and differentiation.
Its involvement in insulin and leptin signaling makes it an important target for research into metabolic disorders, such as obesity and diabetes. By understanding the role of SH2B1 in these processes, researchers can gain insights into potential therapeutic targets for treating these conditions.In conclusion, the SH2B1 Polyclonal Antibody is a valuable tool for researchers investigating the function and regulation of SH2B1 in various physiological and pathological conditions. Its high specificity and reactivity make it a reliable reagent for studying the complex roles of SH2B1 in cellular signaling and metabolism.
Product Name:
SH2B1 Rabbit Polyclonal Antibody
SKU:
CAB5564
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 360-520 of human SH2B1 (NP_056318.2).
This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
25970
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Rat kidney using SH2B1 Rabbit pAb (CAB5564) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
