The SGTB Polyclonal Antibody (PACO39310) offered by Assay Genie is a valuable tool for researchers studying SGTB, a protein that plays a key role in cellular processes. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SGTB protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for investigations in molecular biology and cell signaling pathways.SGTB, also known as an important regulator of protein degradation, is involved in maintaining cellular homeostasis by targeting proteins for degradation via the ubiquitin-proteasome system.
Dysfunction of SGTB has been implicated in various diseases, including neurodegenerative disorders and cancer, making it a promising target for therapeutic interventions. By understanding the mechanisms of SGTB function, researchers can gain insights into disease pathology and potentially develop new treatment strategies. With its high specificity and sensitivity, the SGTB Polyclonal Antibody from Assay Genie is a valuable asset for researchers investigating the role of SGTB in health and disease.
Antibody Name:
SGTB Antibody (PACO39310)
Antibody SKU:
PACO39310
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Small glutamine-rich tetratricopeptide repeat-containing protein β protein (14-304AA)
Immunohistochemistry of paraffin-embedded human colon tissue using PACO39310 at dilution of 1:100.
Background:
Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity.
Synonyms:
Small glutamine-rich tetratricopeptide repeat-containing protein β (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2), SGTB, SGT2
UniProt Protein Function:
SGTB: contains three type 1 and three type 2 tetratricopeptide repeats.Protein type: Unknown functionChromosomal Location of Human Ortholog: 5q12.3Molecular Function: protein binding
