The SGTA Polyclonal Antibody (CAB7306) is a vital tool for researchers studying SGTA, a key protein involved in protein folding and quality control within cells. This antibody, generated in rabbits, demonstrates high specificity and sensitivity towards human samples, making it a reliable choice for Western blot applications. By targeting the SGTA protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an ideal option for investigations in the fields of molecular biology and protein research.SGTA, or small glutamine-rich tetratricopeptide repeat-containing protein alpha, is essential for maintaining proper protein folding and stability, as well as coordinating protein-protein interactions within cells.
Its role in quality control mechanisms highlights its importance in preventing protein misfolding and aggregation, which are implicated in various diseases such as neurodegenerative disorders and cancer. By uncovering the functions of SGTA, researchers can gain valuable insights into cellular homeostasis and develop novel strategies for treating proteinopathies and other related conditions.
Product Name:
[KO Validated] SGTA Rabbit Polyclonal Antibody
SKU:
CAB7306
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SGTA (NP_003012.1).
This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function.
Purification Method:
Affinity purification
Gene ID:
6449
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SGTA antibody (CAB7306) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
