The SGK1 Polyclonal Antibody (CAB1025) is a valuable tool for researchers studying the serum- and glucocorticoid-regulated kinase 1 (SGK1) protein. SGK1 is a serine/threonine protein kinase that plays a key role in cell survival, proliferation, and ion transport. This antibody, raised in rabbits, is highly specific for human samples and is validated for use in Western blot applications.By binding specifically to SGK1, this antibody enables researchers to detect and analyze SGK1 expression in a variety of cell types.
This makes it an ideal choice for studies in cell biology, signal transduction, and cancer research. Understanding the activity of SGK1 is crucial for unraveling its role in various physiological and pathological processes.Overall, the SGK1 Polyclonal Antibody is a high-quality reagent that can help advance our understanding of SGK1 function and its potential as a therapeutic target in diseases such as cancer and cardiovascular disorders.
Product Name:
SGK1 Rabbit Polyclonal Antibody
SKU:
CAB1025
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 172-431 of human SGK1 (NP_005618.2).
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
6446
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SGK1 Rabbit pAb (CAB1025) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
