UniProt Protein Function: | CCDC101: Involved in transcriptional regulation, through association with histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. Specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA- type complexes, required to recruit complexes to H3K4me. May be involved in MYC-mediated oncogenic transformation. Belongs to the SGF29 family.Chromosomal Location of Human Ortholog: 16p11.2Molecular Function: methylated histone residue binding; protein binding |
UniProt Protein Details: | |
NCBI Summary: | CCDC101 is a subunit of 2 histone acetyltransferase complexes: the ADA2A (TADA2A; MIM 602276)-containing (ATAC) complex and the SPT3 (SUPT3H; MIM 602947)-TAF9 (MIM 600822)-GCN5 (KAT2A; MIM 602301)/PCAF (KAT2B; MIM 602303) acetylase (STAGA) complex. Both of these complexes contain either GCN5 or PCAF, which are paralogous acetyltransferases (Wang et al., 2008 [PubMed 18838386]).[supplied by OMIM, Apr 2010] |
UniProt Code: | Q96ES7 |
NCBI GenInfo Identifier: | 74731608 |
NCBI Gene ID: | 112869 |
NCBI Accession: | Q96ES7.1 |
UniProt Secondary Accession: | Q96ES7,Q96MF5 |
UniProt Related Accession: | Q96ES7 |
Molecular Weight: | 33,238 Da |
NCBI Full Name: | SAGA-associated factor 29 |
NCBI Synonym Full Names: | SAGA complex associated factor 29 |
NCBI Official Symbol: | SGF29Â Â |
NCBI Official Synonym Symbols: | STAF36; TDRD29; CCDC101Â Â |
NCBI Protein Information: | SAGA-associated factor 29 |
UniProt Protein Name: | SAGA-associated factor 29 |
UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 101; SAGA complex-associated factor 29 |
Protein Family: | |
UniProt Gene Name: | SGF29Â Â |
UniProt Entry Name: | SGF29_HUMAN |