alpha Sarcoglycan (SGCA) Rabbit Polyclonal Antibody (CAB4109)
- SKU:
- CAB4109
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | alpha Sarcoglycan (SGCA) Rabbit Polyclonal Antibody |
SKU: | CAB4109 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-290 of human alpha Sarcoglycan (alpha Sarcoglycan (SGCA)) (NP_000014.1). |
Sequence: | ITYH AHLQ GHPD LPRW LRYT QRSP HHPG FLYG SATP EDRG LQVI EVTA YNRD SFDT TRQR LVLE IGDP EGPL LPYQ AEFL VRSH DAEE VLPS TPAS RFLS ALGG LWEP GELQ LLNV TSAL DRGG RVPL PIEG RKEG VYIK VGSA SPFS TCLK MVAS PDSH ARCA QGQP PLLS CYDT LAPH FRVD WCNV TLVD KSVP EPAD EVPT PGDG ILEH DPFF CPPT EAPD RDFL VDA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | ADL; DAG2; 50DAG; DMDA2; LGMD2D; LGMDR3; SCARMD1; adhalin; alpha Sarcoglycan (SGCA) |
Positive Sample: | A-549,LO2,293T,Mouse skeletal muscle,Mouse heart,Rat skeletal muscle,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Single-pass type I membrane protein, cytoskeleton, sarcolemma. |
Calculated MW: | 43kDa |
Observed MW: | 43kDa |
This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6442 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |