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alpha Sarcoglycan (SGCA) Rabbit Monoclonal Antibody (CAB19754)

SKU:
CAB19754
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
50DAG
ADL
DAG2
DMDA2
LGMD2D
SCARMD1
adhalin
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:alpha Sarcoglycan (SGCA) Rabbit Monoclonal Antibody
SKU:CAB19754
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 288-387 of human alpha Sarcoglycan (SGCA) (SGCA) (Q16586).
Sequence:VDAL VTLL VPLL VALL LTLL LAYV MCCR REGR LKRD LATS DIQM VHHC TIHG NTEE LRQM AASR EVPR PLST LPMF NVHT GERL PPRV DSAQ VPLI LDQH
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:ADL; DAG2; 50DAG; DMDA2; LGMD2D; LGMDR3; SCARMD1; adhalin; alpha Sarcoglycan (SGCA)
Positive Sample:Rat heart,Rat skeletal muscle
Conjugate:Unconjugated
Cellular Localization:cell-cell junction, cytoplasm, cytoskeleton
Calculated MW:43kDa
Observed MW:48kDa

This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:6442
Clone Number:ARC2280
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using alpha Sarcoglycan (SGCA) (SGCA) Rabbit mAb (CAB19754) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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