The SFXN4 Polyclonal Antibody (PACO01499) is a vital tool for researchers studying SFXN4, a protein involved in mitochondrial function and iron metabolism. This antibody, generated in rabbits, demonstrates high specificity and sensitivity to human samples, making it an excellent choice for Western blot applications. By binding to the SFXN4 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential reagent for studies in mitochondrial biology and iron homeostasis.SFXN4 is a mitochondrial protein that plays a crucial role in iron transport and metabolism, making it a key player in cellular energy production and redox balance. Dysregulation of SFXN4 has been implicated in various human diseases, including neurodegenerative disorders and metabolic conditions.
Research on SFXN4 is essential for gaining insights into these diseases and developing targeted therapies to restore normal mitochondrial function and iron homeostasis.Overall, the SFXN4 Polyclonal Antibody (PACO01499) serves as a valuable tool for scientists investigating the roles of SFXN4 in cellular physiology and pathology. Its high specificity and compatibility with human samples make it an ideal choice for unraveling the complex mechanisms underlying mitochondrial function and iron metabolism, with implications for a wide range of human diseases.
Antibody Name:
SFXN4 Antibody
Antibody SKU:
PACO01499
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human Sideroflexin-4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
SFXN4; BCRM1; Sideroflexin-4; Breast cancer resistance marker 1
UniProt Protein Function:
SFXN4: Potential iron transporter. Belongs to the sideroflexin family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 10q26.11Cellular Component: intracellular membrane-bound organelle; mitochondrial inner membrane; integral to membraneMolecular Function: ion transmembrane transporter activityBiological Process: iron ion homeostasisDisease: Combined Oxidative Phosphorylation Deficiency 18
