SFTPC Rabbit Polyclonal Antibody (CAB11764)
- SKU:
- CAB11764
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | SFTPC Rabbit Polyclonal Antibody |
SKU: | CAB11764 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 59-197 of human SFTPC (NP_003009.2). |
Sequence: | HMSQ KHTE MVLE MSIG APEA QQRL ALSE HLVT TATF SIGS TGLV VYDY QQLL IAYK PAPG TCCY IMKI APES IPSL EALT RKVH NFQM ECSL QAKP AVPT SKLG QAEG RDAG SAPS GGDP AFLG MAVS TLCG EVPL YYI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | SP5; SP-C; PSP-C; SFTP2; SMDP2; BRICD6; SFTPC |
Positive Sample: | Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular space, surface film. |
Calculated MW: | 21kDa |
Observed MW: | 21kDa |
This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 6440 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |