The SFTPA1 Polyclonal Antibody (CAB3133) is a valuable tool for researchers studying the role of SFTPA1, a pulmonary surfactant protein involved in lung function and immune response. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications.SFTPA1 is known for its role in surfactant production in the lungs, helping to reduce surface tension and maintain alveolar stability. In addition, SFTPA1 has been implicated in immune defense mechanisms within the respiratory system, making it a target of interest for studies related to lung diseases and infections.
By using the SFTPA1 Polyclonal Antibody, researchers can detect and analyze SFTPA1 protein levels in various cell types, providing valuable insights into its function and potential implications in respiratory health. This antibody is a valuable tool for investigations into lung diseases, immune responses, and therapeutic strategies targeting SFTPA1.
Product Name:
SFTPA1 Rabbit Polyclonal Antibody
SKU:
CAB3133
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 122-221 of human SFTPA1 (NP_005402.3).
Secreted, extracellular matrix, extracellular space, surface film.
Calculated MW:
26kDa
Observed MW:
30kDa
This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
653509
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SFTPA1 Rabbit pAb (CAB3133) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
