The SFTA3 Polyclonal Antibody (PAC029864) is a valuable tool for researchers studying SFTA3, a protein associated with surfactant production in the lungs. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in Western blot applications. By binding to the SFTA3 protein, this antibody allows for the detection and analysis of SFTA3 expression in various cell types, making it an ideal choice for studies in pulmonary physiology and respiratory diseases.SFTA3 plays a crucial role in maintaining proper lung function by promoting the production and function of pulmonary surfactant, a vital substance that reduces surface tension in the alveoli and prevents lung collapse.
Dysregulation of SFTA3 expression has been linked to various lung disorders, including pulmonary fibrosis and respiratory distress syndrome, highlighting its importance in respiratory health. Research on SFTA3 could provide valuable insights into the pathogenesis of these conditions and potentially lead to the development of novel therapeutic approaches targeting surfactant dysfunction.
Antibody Name:
SFTA3 Antibody (PACO29864)
Antibody SKU:
PACO29864
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Surfactant-associated protein 3 protein (1-94AA)
Surfactant-associated protein 3 (Surfactant-associated protein H) (SP-H), SFTA3, SFTPH
UniProt Protein Function:
SFTA3: Induced by lipopolysaccharides (LPS). Down-regulated by cytokines IL1B and IL23. {ECO:0000269|PubMed:24743970}Chromosomal Location of Human Ortholog: 14q13.3Cellular Component: clathrin-coated endocytic vesicle; endoplasmic reticulum membrane; extracellular region; lamellar bodyBiological Process: cellular protein metabolic process
