The SFRS9 Polyclonal Antibody (CAB12538) is a valuable tool for researchers studying SFRS9, a splicing factor involved in mRNA processing. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the SFRS9 protein, this antibody enables precise detection and analysis of SFRS9 in various cell types, making it ideal for investigations in molecular biology and gene expression studies.SFRS9, also known as serine/arginine-rich splicing factor 9, plays a crucial role in alternative splicing of pre-mRNA, ultimately regulating gene expression and protein diversity.
Its involvement in mRNA processing makes it a key player in cellular functions, with implications in various physiological and pathological processes. Research on SFRS9 is important for understanding its impact on gene regulation and identifying potential therapeutic targets in diseases related to aberrant splicing.
Product Name:
SFRS9 Rabbit Polyclonal Antibody
SKU:
CAB12538
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human SFRS9 (NP_003760.1).
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two pseudogenes, one on chromosome 15 and the other on chromosome 21, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8683
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SRSF9 antibody (CAB12538) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
