The SFRP5 Polyclonal Antibody (CAB16734) is a valuable tool for research involving SFRP5, a secreted frizzled-related protein that plays a critical role in regulating Wnt signaling pathways. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the SFRP5 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for studying the role of SFRP5 in various biological processes.SFRP5 is known for its involvement in metabolic diseases such as obesity and diabetes, as well as its potential as a biomarker for cardiovascular disease.
This protein is also implicated in cancer progression, making it a promising target for therapeutic interventions. Understanding the function of SFRP5 is crucial for unraveling its complex role in disease pathogenesis and ultimately developing effective treatment strategies. The SFRP5 Polyclonal Antibody is a reliable reagent for researchers investigating the impact of SFRP5 dysregulation in health and disease.
Product Name:
SFRP5 Rabbit Polyclonal Antibody
SKU:
CAB16734
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-317 of human SFRP5 (NP_003006.2).
Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.
Purification Method:
Affinity purification
Gene ID:
6425
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SFRP5 antibody (CAB16734) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
