The SFRP4 Rabbit Monoclonal Antibody (CAB4189) is a valuable tool for researchers studying the Secreted Frizzled-Related Protein 4 (SFRP4) molecule, which is involved in regulating Wnt signaling pathways. This antibody, developed using rabbit monoclonal technology, exhibits high reactivity with human samples and has been validated for use in Western blot applications.SFRP4 is known for its role in modulating cell proliferation, differentiation, and migration, making it a key player in various biological processes including development, tissue homeostasis, and disease progression.
By targeting the SFRP4 protein, researchers can gain insights into the intricate mechanisms of Wnt signaling and its impact on cancer, tissue regeneration, and stem cell biology.With its specificity and sensitivity, the SFRP4 Rabbit Monoclonal Antibody is an essential tool for immunology and cancer research studies aimed at deciphering the functions of SFRP4 and its potential as a therapeutic target in various diseases.
Product Name:
SFRP4 Rabbit Monoclonal Antibody
SKU:
CAB4189
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 201-300 of human SFRP4 (Q6FHJ7).
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.
Purification Method:
Affinity purification
Gene ID:
6424
Clone Number:
ARC0923
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SFRP4 Rabbit mAb (CAB4189) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
