The SFRP4 Polyclonal Antibody (CAB6409) is a valuable tool for researchers studying the secreted frizzled-related protein 4 (SFRP4), a protein involved in the Wnt signaling pathway. This antibody, produced in rabbits, is highly specific to human samples and is suitable for use in Western blot applications. By binding to SFRP4, researchers can detect and analyze this important protein in various cell types, making it an ideal choice for studies in developmental biology, cancer research, and regenerative medicine.SFRP4 is known to play a crucial role in regulating cell growth, differentiation, and tissue regeneration by modulating the Wnt signaling pathway.
Dysregulation of this pathway has been linked to various diseases, including cancer and developmental disorders. Therefore, understanding the function of SFRP4 is essential for developing new therapies targeting the Wnt signaling pathway in these pathological conditions.Overall, the SFRP4 Polyclonal Antibody is a reliable tool for investigating the role of SFRP4 in various biological processes, providing valuable insights into Wnt signaling pathway modulation and potential therapeutic strategies for related diseases.
Product Name:
SFRP4 Rabbit Polyclonal Antibody
SKU:
CAB6409
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-346 of human SFRP4 (NP_003005.2).
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.
Purification Method:
Affinity purification
Gene ID:
6424
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SFRP4 antibody (CAB6409) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
