The SFRP2 Polyclonal Antibody (CAB5383) is a powerful tool for researchers studying SFRP2, a secreted protein known for its involvement in cellular growth and differentiation processes. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the SFRP2 protein, this antibody enables researchers to detect and analyze its expression in various cell types, making it an essential component in studies related to developmental biology, tissue regeneration, and cancer research.SFRP2, also known as secreted frizzled-related protein 2, is a key player in regulating Wnt signaling pathways, which are crucial for normal development and control of cell proliferation.
Dysregulation of SFRP2 has been implicated in various diseases, including cancer, fibrosis, and cardiovascular disorders. By studying the function and expression of SFRP2 using this antibody, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.Overall, the SFRP2 Polyclonal Antibody offers researchers a reliable tool to investigate the role of SFRP2 in cellular processes and disease pathogenesis, opening up new possibilities for advancing our understanding and treatment of various conditions.
Product Name:
SFRP2 Rabbit Polyclonal Antibody
SKU:
CAB5383
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-295 of human SFRP2 (NP_003004.1).
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.
Purification Method:
Affinity purification
Gene ID:
6423
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SFRP2 antibody (CAB5383) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
