The SFRP2 Polyclonal Antibody (CAB12959) is a valuable tool for researchers studying SFRP2, a secreted protein involved in various biological processes, including cell proliferation, differentiation, and tissue regeneration. This antibody is raised in rabbits and is highly specific for detecting SFRP2 in human samples, making it a reliable choice for Western blot applications.SFRP2, also known as Secreted frizzled-related protein 2, plays a crucial role in modulating the Wnt signaling pathway, which is involved in embryonic development, tissue homeostasis, and tumorigenesis.
Dysregulation of SFRP2 has been implicated in various diseases, including cancer, fibrosis, and cardiovascular disorders, highlighting its potential as a therapeutic target.By using the SFRP2 Polyclonal Antibody, researchers can specifically detect and measure SFRP2 levels in different cell types and tissues, aiding in the understanding of its function and signaling pathways. This antibody is a valuable asset for studies in developmental biology, cancer research, and regenerative medicine, providing important insights into the role of SFRP2 in health and disease.
Product Name:
SFRP2 Rabbit Polyclonal Antibody
SKU:
CAB12959
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SFRP2 (NP_003004.1).
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.
Purification Method:
Affinity purification
Gene ID:
6423
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse pancreas, using SFRP2 antibody (CAB12959) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
