SFRP1 Rabbit Polyclonal Antibody (CAB2911)
- SKU:
- CAB2911
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | SFRP1 Rabbit Polyclonal Antibody |
SKU: | CAB2911 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-314 of human SFRP1 (NP_003003.3). |
Sequence: | SASE YDYV SFQS DIGP YQSG RFYT KPPQ CVDI PADL RLCH NVGY KKMV LPNL LEHE TMAE VKQQ ASSW VPLL NKNC HAGT QVFL CSLF APVC LDRP IYPC RWLC EAVR DSCE PVMQ FFGF YWPE MLKC DKFP EGDV CIAM TPPN ATEA SKPQ GTTV CPPC DNEL KSEA IIEH LCAS EFAL RMKI KEVK KENG DKKI VPKK KKPL KLGP IKKK DLKK LVLY LKNG ADCP CHQL DNLS HHFL IMGR KVKS QYLL TAIH KWDK KNKE FKNF MKKM KNHE CPTF QSVF K |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 |
Synonyms: | FRP; FRP1; FrzA; FRP-1; SARP2; SFRP1 |
Positive Sample: | NCI-H460,293T,SKOV3,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 35kDa |
Observed MW: | 35kDa |
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
Purification Method: | Affinity purification |
Gene ID: | 6422 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |