The SFPQ Rabbit Monoclonal Antibody (CAB3494) is a high-quality antibody specifically designed for research involving the splicing factor, proline- and glutamine-rich (SFPQ) protein. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.The SFPQ protein plays crucial roles in regulating RNA splicing, DNA repair, and gene expression, making it a key player in cellular processes such as development, differentiation, and stress response. The SFPQ Rabbit Monoclonal Antibody allows for the detection and analysis of SFPQ protein in different cell types, providing researchers with a valuable tool for studying the molecular mechanisms underlying these processes.
With its high specificity and sensitivity, the SFPQ Rabbit Monoclonal Antibody is ideal for investigations in molecular biology, genetics, and neuroscience. By targeting the SFPQ protein, researchers can gain insights into its functions and potential implications in diseases such as cancer, neurodegenerative disorders, and autoimmune conditions. This antibody is a valuable asset for advancing research in these fields and ultimately contributing to the development of innovative therapeutic approaches.
Product Name:
SFPQ Rabbit Monoclonal Antibody
SKU:
CAB3494
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-707 of human SFPQ (P23246).
Enables DNA binding activity; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; and regulation of transcription by RNA polymerase II. Acts upstream of or within double-strand break repair via homologous recombination. Located in chromatin; nuclear matrix; and paraspeckles.
Purification Method:
Affinity purification
Gene ID:
6421
Clone Number:
ARC0788
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using SFPQ Rabbit mAb (CAB3494) at 1:200 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
