The SFPQ Polyclonal Antibody (CAB0958) is a valuable tool for researchers studying the function of the SFPQ protein, a key player in RNA processing and regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SFPQ protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential reagent for studies in molecular biology and gene expression research.SFPQ, also known as splicing factor proline/glutamine-rich, is a multifunctional protein involved in various cellular processes, including RNA splicing and transcriptional regulation.
Its role in RNA metabolism and gene expression makes it a crucial target for investigating diseases such as neurological disorders, cancer, and developmental abnormalities. Understanding the function of SFPQ is essential for unraveling its contribution to these conditions and identifying potential therapeutic interventions that target this protein.
Product Name:
SFPQ Rabbit Polyclonal Antibody
SKU:
CAB0958
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 578-707 of human SFPQ (NP_005057.1).
Enables DNA binding activity; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; and regulation of transcription by RNA polymerase II. Acts upstream of or within double-strand break repair via homologous recombination. Located in chromatin; nuclear matrix; and paraspeckles.
Purification Method:
Affinity purification
Gene ID:
6421
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SFPQ Rabbit pAb (CAB0958) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
