The SFN Polyclonal Antibody (CAB1026) is a valuable tool for researchers studying SFN, a protein involved in cell signaling and regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the SFN protein, researchers can accurately detect and analyze SFN levels in various cell types, making it an ideal choice for studies in cancer biology and cellular signaling pathways.
SFN, also known as 14-3-3 sigma, plays a crucial role in cell cycle regulation, apoptosis, and DNA repair mechanisms. Dysregulation of SFN has been implicated in various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions. Understanding the function and regulation of SFN is essential for developing targeted therapies aimed at manipulating cellular processes affected by SFN dysfunction.
Product Name:
14-3-3 sigma Rabbit Polyclonal Antibody
SKU:
CAB1026
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human 14-3-3 sigma (NP_006133.1).
This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis.
Purification Method:
Affinity purification
Gene ID:
2810
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using 14-3-3 sigma Rabbit pAb (CAB1026) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
