SF3B2 Rabbit Polyclonal Antibody (CAB5875)
- SKU:
- CAB5875
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | SF3B2 Rabbit Polyclonal Antibody |
SKU: | CAB5875 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 616-895 of human SF3B2 (NP_006833.2). |
Sequence: | SLGM PVGP NAHK VPPP WLIA MQRY GPPP SYPN LKIP GLNS PIPE SCSF GYHA GGWG KPPV DETG KPLY GDVF GTNA AEFQ TKTE EEEI DRTP WGEL EPSD EESS EEEE EEES DEDK PDET GFIT PADS GLIT PGGF SSVP AGME TPEL IELR KKKI EEAM DGSE TPQL FTVL PEKR TATV GGAM MGST HIYD MSTV MSRK GPAP ELQG VEVA LAPE ELEL DPMA MTQK YEEH VREQ QAQV EKED FSDM VAEH AAKQ KQKK RKAQ PQDS RGGS KKYK EFKF |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CFM; HFM; Cus1; SF3b1; SAP145; SF3B145; SF3b150; SF3B2 |
Positive Sample: | HeLa,MCF7,SW620,A375,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 100kDa |
Observed MW: | 140kDa |
This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.
Purification Method: | Affinity purification |
Gene ID: | 10992 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |