The SF3A1 Polyclonal Antibody (CAB4399) is a valuable tool for researchers studying SF3A1, a key component of the splicing factor 3a complex involved in RNA splicing. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SF3A1 protein, researchers can accurately detect and analyze its expression in various cell types, making it ideal for studies in molecular biology and gene regulation.
SF3A1 plays a crucial role in the splicing process, ensuring the accurate removal of introns from pre-mRNA molecules. Dysregulation of SF3A1 has been linked to various diseases, including cancer and genetic disorders, highlighting its importance in gene expression and cellular function. By investigating the function of SF3A1, researchers can gain insights into disease mechanisms and potentially identify novel therapeutic targets for treatment.
Product Name:
SF3A1 Rabbit Polyclonal Antibody
SKU:
CAB4399
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 715-785 of human SF3A1 (Q15459).
This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing.
Purification Method:
Affinity purification
Gene ID:
10291
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SF3A1 Rabbit pAb (CAB4399) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
