The SF2/ASF Rabbit Monoclonal Antibody (CAB4091) is a valuable tool for researchers studying alternative splicing, a crucial process in gene expression regulation. This antibody, generated from rabbit monoclonal cells, is highly specific and reactive with human samples, making it ideal for Western blot applications.SF2/ASF, also known as splicing factor 2/alternative splicing factor, plays a key role in determining the outcome of alternative splicing events, leading to the production of diverse protein isoforms from a single gene. Dysregulation of alternative splicing is associated with various diseases, including cancer and neurological disorders, making SF2/ASF a target of interest in molecular and cellular biology research.
By using the SF2/ASF Rabbit Monoclonal Antibody, researchers can accurately detect and analyze SF2/ASF protein levels in different cell types, shedding light on its function in alternative splicing regulation. This antibody is a valuable tool for investigating the molecular mechanisms underlying gene expression diversity and its implications in disease development.
Product Name:
SRSF1/SF2/ASF Rabbit Monoclonal Antibody
SKU:
CAB4091
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRSF1/SF2/ASF (NP_008855.1).
This gene encodes a member of the arginine/serine-rich splicing factor protein family. The encoded protein can either activate or repress splicing, depending on its phosphorylation state and its interaction partners. Multiple transcript variants have been found for this gene. There is a pseudogene of this gene on chromosome 13.
Purification Method:
Affinity purification
Gene ID:
6426
Clone Number:
ARC51453
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SRSF1/SF2/ASF Rabbit mAb (CAB4091) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
