SETMAR Rabbit Polyclonal Antibody (CAB6738)
- SKU:
- CAB6738
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SETMAR Rabbit Polyclonal Antibody |
SKU: | CAB6738 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human SETMAR (NP_006506.3). |
Sequence: | KPEA PTEQ LDVA CGQE NLPV GAWP PGAA PAPF QYTP DHVV GPGA DIDP TQIT FPGC ICVK TPCL PGTC SCLR HGEN YDDN SCLR DIGS GGKY AEPV FECN VLCR CSDH CRNR VVQK GLQF HFQV FKTH KKGW GLRT LEFI PKGR FVCE YAGE VLGF SEVQ RRIH LQTK SDSN YIIA IREH VYNG QVME TFVD PTYI GNIG RFLN HSCE PNLL MIPV RIDS MVPK LALF AAKD IVPE EELS YDYS GRYL NLTV SEDK ERLD HGKL RKPC YCGA KSCT AFLP F |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | Mar1; METNASE; SETMAR |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 78kDa |
Observed MW: | Refer to Figures |
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 6419 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |