SETDB2 Rabbit Polyclonal Antibody (CAB7391)
- SKU:
- CAB7391
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | SETDB2 Rabbit Polyclonal Antibody |
SKU: | CAB7391 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 148-378 of human SETDB2 (NP_114121.2). |
Sequence: | SGAC LMKM PLNL KGEN PLQL PIKC HFQR RHAK TNSH SSAL HVSY KTPC GRSL RNVE EVFR YLLE TECN FLFT DNFS FNTY VQLA RNYP KQKE VVSD VDIS NGVE SVPI SFCN EIDS RKLP QFKY RKTV WPRA YNLT NFSS MFTD SCDC SEGC IDIT KCAC LQLT ARNA KTSP LSSD KITT GYKY KRLQ RQIP TGIY ECSL LCKC NRQL CQNR VVQH GPQV RLQV FKTE QKG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CLLD8; CLLL8; KMT1F; C13orf4; SETDB2 |
Positive Sample: | Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 82kDa |
Observed MW: | 100kDa |
This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 83852 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |