The SETD9 Polyclonal Antibody (PAC038578) is a research tool designed for studying the SETD9 protein, a histone methyltransferase involved in epigenetic regulation. This antibody, produced using rabbits as the host species, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.SETD9 plays a crucial role in the modification of histones, specifically in the methylation of lysine 4 on histone H3. Dysregulation of SETD9 function has been implicated in various diseases, including cancer and developmental disorders. The SETD9 Polyclonal Antibody enables the detection and analysis of SETD9 protein levels in different cell types, making it a valuable tool for research in the fields of epigenetics and cancer biology.
By understanding the role of SETD9 in chromatin modification and gene regulation, researchers can gain insights into the mechanisms underlying disease pathogenesis and potentially identify novel therapeutic targets for intervention. Studying SETD9 with this antibody may lead to advancements in the development of targeted therapies for diseases associated with epigenetic dysregulation.
Antibody Name:
SETD9 Antibody (PACO38578)
Antibody SKU:
PACO38578
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human SET domain-containing protein 9 protein (1-299AA)
Western blot. All lanes: SETD9 antibody at 6µg/ml + K562 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 35, 31 kDa. Observed band size: 35 kDa.
Synonyms:
SET domain-containing protein 9 (EC 2.1.1.-), SETD9, C5orf35
UniProt Protein Function:
SETD9: 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 5q11.2Molecular Function: methyltransferase activityBiological Process: methylation
