The SETD7 Rabbit Monoclonal Antibody (CAB9225) is a cutting-edge tool for researchers studying the SETD7 protein, a key epigenetic regulator involved in various biological processes. This highly specific antibody, developed using rabbit monoclonal technology, exhibits exceptional reactivity with human samples and is validated for use in immunohistochemistry (IHC) and immunofluorescence (IF) applications.SETD7, a histone methyltransferase enzyme, plays a pivotal role in gene regulation, cell cycle control, and cellular differentiation. Dysregulation of SETD7 has been linked to cancer, diabetes, and cardiovascular diseases, making it a promising target for therapeutic interventions. By detecting and quantifying SETD7 expression in tissue samples, researchers can gain valuable insights into its function and potential implications in disease development and progression.
Utilizing the SETD7 Rabbit Monoclonal Antibody in experimental studies enables precise visualization and analysis of SETD7 localization and activity within cells, providing valuable data for understanding its biological functions and underlying mechanisms. This antibody is a valuable resource for investigations in molecular biology, cancer research, and epigenetics, offering researchers a powerful tool for advancing scientific knowledge and drug discovery efforts related to SETD7-mediated pathways.
Product Name:
SETD7 Rabbit Monoclonal Antibody
SKU:
CAB9225
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SETD7 (Q8WTS6).
Enables histone-lysine N-methyltransferase activity and p53 binding activity. Involved in peptidyl-lysine dimethylation and peptidyl-lysine monomethylation. Acts upstream of or within cellular response to DNA damage stimulus and heterochromatin organization. Located in chromosome and nucleolus.
Purification Method:
Affinity purification
Gene ID:
80854
Clone Number:
ARC1483
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using SETD7 Rabbit mAb (CAB9225) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
