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SETD7 Monoclonal Antibody [Ps4E5AT] (CPAB0125)

SKU:
CPAB0125
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
Ps4E5AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

SETD7 Monoclonal Antibody [Ps4E5AT] (CPAB0125)

The SETD7 Polyclonal Antibody (CPAB0125) is a valuable tool for research involving the SETD7 protein, a histone methyltransferase known for its role in various cellular processes such as gene regulation and cell cycle control. This antibody, raised in rabbits, is highly specific and reacts with human, mouse, and rat samples, making it versatile for different experimental models.SETD7 is involved in epigenetic modifications that influence gene expression, making it a key player in cellular development and differentiation. The SETD7 Polyclonal Antibody binds specifically to SETD7, allowing for accurate detection and analysis in a variety of cell types and tissues.

This makes it ideal for studies in molecular biology, cell signaling, and epigenetics.The importance of SETD7 in regulating gene expression and cellular processes underscores its relevance in various disease contexts, including cancer and developmental disorders. By understanding the function of SETD7, researchers can gain insights into potential therapeutic targets and mechanisms for intervention. The SETD7 Polyclonal Antibody is a valuable tool for investigating the biology of SETD7 and its implications in health and disease.

Product Name:SETD7 Antibody
Product Sku:CPAB0125
Size:5μg
Host Species:Mouse
Immunogen:Anti-human SETD7 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SETD7 amino acids 1-366 purified from Ecoli.
Clone:Ps4E5AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:SETD7 antibody was purified from hybridoma cell supernatant by protein-A affinity chromatography.
Isotype:IgG2b
Background:Set 7/9 is a histone methyltransferase (HMTase) that transfers methyl groups to Lys4 of histone H3, in complex with S-adenosyl-L-methionine (AdoMet). The methylation of lysine residues of histones plays a critical role in the regulation of chromatin structure and gene expression. Acetylation, phosphorylation and methylation of the amino-terminal tails of histone are thought to be involved in the regulation of chromatin structure and function. The enzymes identified in the methylation of specific lysine residue on histones belong to the SET family with just one exception. Set7/9, unlike most other SET proteins, is exclusively a mono-methylase.
Synonyms:Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7, EC 2.1.1.43, Histone H3-K4 methyltransferase, H3-K4-HMTase, SET domain-containing protein 7, Set9, SET7/9, SETD7.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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