The SETD6 Polyclonal Antibody (CAB7242) is a valuable tool for researchers studying the SETD6 protein, a histone methyltransferase involved in epigenetic regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting SETD6 in human samples, making it suitable for use in Western blot experiments.SETD6 plays a crucial role in chromatin remodeling and gene expression, making it a key player in cellular processes such as DNA repair, cell cycle regulation, and development. Dysregulation of SETD6 has been linked to various diseases, including cancer, neurodegenerative disorders, and developmental defects, highlighting its importance as a therapeutic target.
By utilizing the SETD6 Polyclonal Antibody, researchers can accurately detect and analyze SETD6 expression in different cell types, providing valuable insights into its function and potential role in disease pathways. This antibody is an essential tool for advancing research in the fields of epigenetics, cancer biology, and drug discovery.
Product Name:
SETD6 Rabbit Polyclonal Antibody
SKU:
CAB7242
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 301-473 of human SETD6 (NP_001153777.1).
This gene encodes a methyltransferase that adds a methyl group to the histone H2AZ, which is involved in nuclear receptor-dependent transcription. The protein also interacts with several endogenous proteins which are involved in nuclear hormone receptor signaling. A related pseudogene is located on chromosome 2. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
79918
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SETD6 Rabbit pAb (CAB7242) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
