The SETD6 Monoclonal Antibody is a cutting-edge tool for researchers investigating the role of SETD6, an important enzyme involved in the regulation of gene expression and epigenetic modifications. This antibody, produced through monoclonal technology, exhibits high specificity and sensitivity towards SETD6 protein in human samples, making it ideal for use in various research applications such as immunoprecipitation and immunofluorescence.SETD6 is known for its role in histone methylation and chromatin remodeling, ultimately impacting gene transcription and cell fate.
Dysregulation of SETD6 has been linked to various diseases, including cancer and neurological disorders, highlighting its potential as a therapeutic target. By utilizing the SETD6 Monoclonal Antibody, researchers can gain valuable insights into the molecular mechanisms underlying these diseases and explore new avenues for drug development and personalized medicine.
Product Name:
SETD6 Monoclonal Antibody
SKU:
CAB22262
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 310-473 of human SETD6 (NP_001153777.1).
This gene encodes a methyltransferase that adds a methyl group to the histone H2AZ, which is involved in nuclear receptor-dependent transcription. The protein also interacts with several endogenous proteins which are involved in nuclear hormone receptor signaling. A related pseudogene is located on chromosome 2. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
79918
Clone Number:
ARC55206
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SETD6 antibody (CAB22262) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
