The SETD5 Polyclonal Antibody (CAB7304) is a valuable tool for researchers investigating the SETD5 protein, a histone methyltransferase involved in chromatin remodeling and gene regulation. This antibody, raised in rabbits, exhibits high specificity and sensitivity for detecting SETD5 in human samples, making it ideal for use in Western blot applications.SETD5 plays a critical role in epigenetic regulation, impacting gene expression and ultimately influencing cell function and development.
Dysregulation of SETD5 has been linked to various diseases, including developmental disorders and cancer. By using the SETD5 Polyclonal Antibody, researchers can accurately study the expression and localization of SETD5 in different cell types and tissues, leading to a better understanding of its biological functions and potential therapeutic interventions.
Product Name:
SETD5 Rabbit Polyclonal Antibody
SKU:
CAB7304
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1054-1153 of human SETD5 (NP_001073986.1).
This function of this gene has yet to be determined but based on sequence similarity to other SET domain proteins it may function as a histone methyltransferase. Mutations in this gene have been associated with an autosomal dominant form of intellectual disability. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
55209
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SETD5 Rabbit pAb (CAB7304) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
