The SETD5 Polyclonal Antibody (CAB14140) is an essential tool for researchers studying the SETD5 protein, which plays a critical role in chromatin organization, gene expression, and cellular differentiation. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for Western blot analysis.SETD5 is a histone methyltransferase known for its involvement in regulating gene expression and influencing cell fate decisions. Dysregulation of SETD5 has been linked to developmental disorders and various cancers, making it a promising target for therapeutic interventions.
By detecting and quantifying SETD5 protein levels, researchers can gain valuable insights into its function and potentially identify novel therapeutic targets for treating diseases related to its dysregulation.With its ability to specifically recognize SETD5 in various cell types, the SETD5 Polyclonal Antibody is invaluable for advancing research in epigenetics, developmental biology, and oncology. By elucidating the mechanisms underlying SETD5-mediated processes, researchers can pave the way for innovative treatment strategies and personalized medicine approaches in the future.
Product Name:
SETD5 Rabbit Polyclonal Antibody
SKU:
CAB14140
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 520-740 of human SETD5 (NP_001073986.1).
This function of this gene has yet to be determined but based on sequence similarity to other SET domain proteins it may function as a histone methyltransferase. Mutations in this gene have been associated with an autosomal dominant form of intellectual disability. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
55209
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of MCF-7 cells using SETD5 antibody (CAB14140). Blue: DAPI for nuclear staining.