SETD2 Rabbit Polyclonal Antibody (CAB11757)
- SKU:
- CAB11757
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | SETD2 Rabbit Polyclonal Antibody |
SKU: | CAB11757 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 803-1103 of human SETD2 (NP_054878.5). |
Sequence: | SLCN SEAE NIEP SVMK ISSN SFMN VHLE SKPV ICDS RNLT DHSK FACE EYKQ SIGS TSSA SVNH FDDL YQPI GSSG IASS LQSL PPGI KVDS LTLL KCGE NTSP VLDA VLKS KKSS EFLK HAGK ETIV EVGS DLPD SGKG FASR ENRR NNGL SGKC LQEA QEEG NSIL PERR GRPE ISLD ERGE GGHV HTSD DSEV VFSS CDLN LTME DSDG VTYA LKCD SSGH APEI VSTV HEDY SGSS ESSN DESD SEDT DSDD SSIP RNRL QSVV VVPK NSTL PMEE TSPC SSRS SQSY RHYS DHWE D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LLS; HYPB; SET2; HIF-1; HIP-1; KMT3A; MRD70; RAPAS; HBP231; HSPC069; p231HBP; SETD2 |
Positive Sample: | HeLa,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 288kDa |
Observed MW: | 288kDa |
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
Purification Method: | Affinity purification |
Gene ID: | 29072 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |