The CD300A Rabbit Monoclonal Antibody (CAB9173) is a high-quality reagent designed for research involving CD300A, a cell surface molecule known for its role in immune regulation. This antibody, raised in rabbits, offers exceptional reactivity with human samples and has been validated for Western blot applications. By specifically binding to the CD300A protein, researchers can easily detect and analyze this molecule in various cell types, making it an ideal tool for studies in immunology and cancer research.CD300A, also referred to as an immune inhibitory receptor, is a crucial player in immune homeostasis by modulating inflammation and inhibiting allergic reactions. Its pivotal role in immune response modulation positions it as a valuable target for investigations into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Unveiling the mechanisms underlying CD300A activity is essential for the development of innovative therapies that either harness or manipulate immune function in these disease contexts.Overall, the CD300A Rabbit Monoclonal Antibody (CAB9173) offers researchers a reliable and effective means to explore the functions and implications of CD300A in various pathological and physiological settings. Its high specificity and sensitivity make it an indispensable tool for advancing our understanding of immune regulation and disease pathogenesis.
Product Name:
SET/TAF1 Rabbit Monoclonal Antibody
SKU:
CAB9173
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-290 of human SET/TAF1 (Q01105).
The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6418
Clone Number:
ARC1462
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using SET/TAF1 Rabbit mAb (CAB9173) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
