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SET/TAF1 Rabbit Polyclonal Antibody (CAB12513)

SKU:
CAB12513
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:SET/TAF1 Rabbit Polyclonal Antibody
SKU:CAB12513
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 146-277 of human SET/TAF1 (NP_003002.2).
Sequence:NESG DPSS KSTE IKWK SGKD LTKR SSQT QNKA SRKR QHEE PESF FTWF TDHS DAGA DELG EVIK DDIW PNPL QYYL VPDM DDEE GEGE EDDD DDEE EEGL EDID EEGD EDEG EEDE DDDE GEEG EEDE GEDD
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:2PP2A; IGAAD; MRD58; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA; SET/TAF1
Positive Sample:HeLa,293T,BT-474,Mouse spleen
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Endoplasmic reticulum, Nucleus, cytosol, nucleoplasm.
Calculated MW:33kDa
Observed MW:33kDa

The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:6418
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using SET/TAF1 antibody (CAB12513) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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