SET/TAF1 Rabbit Polyclonal Antibody (CAB12502)
- SKU:
- CAB12502
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | SET/TAF1 Rabbit Polyclonal Antibody |
SKU: | CAB12502 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 146-277 of human SET/TAF1 (NP_003002.2). |
Sequence: | NESG DPSS KSTE IKWK SGKD LTKR SSQT QNKA SRKR QHEE PESF FTWF TDHS DAGA DELG EVIK DDIW PNPL QYYL VPDM DDEE GEGE EDDD DDEE EEGL EDID EEGD EDEG EEDE DDDE GEEG EEDE GEDD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | 2PP2A; IGAAD; MRD58; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA; SET/TAF1 |
Positive Sample: | HeLa,293T,BT-474,HL-60,NIH/3T3,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum, Nucleus, cytosol, nucleoplasm. |
Calculated MW: | 33kDa |
Observed MW: | 34kDa |
The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6418 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |