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SETBP1 Rabbit Polyclonal Antibody (CAB7212)

SKU:
CAB7212
Product Type:
Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 11 Anti-SETBP1 Antibody CAB7212
  • Cell Biology Antibodies 11 Anti-SETBP1 Antibody CAB7212
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:SETBP1 Rabbit Polyclonal Antibody
SKU:CAB7212
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human SETBP1 (NP_001123582.1).
Sequence:MESR ETLS SSRQ RGGE SDFL PVSS AKPP AAPG CAGE PLLS TPGP GKGI PVGG ERME PEEE DELG SGRD VDSN SNAD SEKW VAGD GLEE QEFS IKEA NFTE GSLK LKIQ TTKR AKKP PKNL ENYI CPPE IKIT IKQS GDQK VSRA GKNS KATK EEER SHSK KKLL TASD LAAS DLKG FQPQ IKDS SKEE VWKR RGGQ GIPF KKQF LSQE RAMC FSCP RNPF PAKP GSLT LPFH SEPA VWAQ EV
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:100
Synonyms:SEB; MRD29; SETBP1
Positive Sample:NCI-H460, HeLa
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:175kDa
Observed MW:175kDa

This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:26040
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using SETBP1 Rabbit pAb (CAB7212) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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