The Set Binding Protein Polyclonal Antibody (CAB7212) is a valuable tool for researchers studying Set Binding Protein, a molecule involved in various cellular processes, including gene regulation and chromatin remodeling. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications.Set Binding Protein, also known as SetBP1, is a key player in the regulation of gene expression and has been linked to cancer development and progression. By targeting Set Binding Protein with this antibody, researchers can detect and analyze its expression levels in different cell types, providing insights into its role in cancer biology and potential therapeutic targets.
The Set Binding Protein Polyclonal Antibody is an essential tool for investigating the functions and mechanisms of Set Binding Protein in various biological contexts. Its high specificity and sensitivity make it ideal for studies in cancer research, epigenetics, and chromatin biology. By utilizing this antibody, researchers can advance their understanding of Set Binding Protein and its implications for human health and disease.
Product Name:
SETBP1 Rabbit Polyclonal Antibody
SKU:
CAB7212
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human SETBP1 (NP_001123582.1).
This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
26040
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SETBP1 Rabbit pAb (CAB7212) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
